Roadrunners in the Minor Leagues
| Name | Organization | Years at UTSA | Draft Round | MiLB Status | Bio |
| Justin Anderson | Texas Rangers | 2012-14 | 14 | Round Rock (AAA) | Link |
| Bryan Arias | Houston Astros | 2016-19 | 28 | Corpus Christi (AA) | Link |
| Derek Craft | New York Yankees | 2016-18 | 16 | Somerset (AA) | Link |
| Chance Kirby | Detroit Tigers | 2015-18 | 25 | Erie (AA) | Link |
| Chris Muller | Tampa Bay Rays | 2017 | 17 | Durham (AAA) | Link |
| Karan Patel | Chicago White Sox | 2016-19 | 7 | Winston-Salem (+A) | Link |
| Nick Thornquist | Chicago White Sox | 2019-21 | UDFA | Arizona (Rookie) | Link |